|
|
7,8-dihydroneopterin + O2 <=> dihydroxanthopterin + formate + glycolaldehyde + H+
|
1.13.11.81
7,8-dihydroneopterin oxygenase
|
–
|
| |
BRENDA:
BR51490
KEGG:
R11037
MetaCyc:
RXN-16480
|
|
|
|
4a-hydroxytetrahydrobiopterin <=> dihydrobiopterin + H2O
|
4.2.1.96
4a-hydroxytetrahydrobiopterin dehydratase
|
–
|
| |
BRENDA:
BR468;
BS2138
KEGG:
R04734
|
|
|
|
4-(beta-D-ribofuranosyl)aminobenzene-5''-phosphate + 6-hydroxymethyl-7,8-dihydropterin_diphosphate <=> 7,8-dihydropterin-6-ylmethyl-4-(beta-D-ribofuranosyl)aminobenzene_5''-phosphate + diphosphate
|
2.5.1.105
7,8-dihydropterin-6-yl-methyl-4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase
|
–
|
| |
BRENDA:
BR50431
KEGG:
R10339
MetaCyc:
RXN-10009
|
|
|
|
7,8-dihydroneopterin <=> 7,8-dihydro-L-monapterin
|
5.1.99.7
dihydroneopterin triphosphate 2'-epimerase
5.1.99.8
7,8-dihydroneopterin epimerase
|
–
–
|
| |
BRENDA:
BR51541
KEGG:
R11073
MetaCyc:
RXN-10856
|
|
|
|
tetrahydrobiopterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
|
–
|
| |
BRENDA:
BR50007
KEGG:
R08208
MetaCyc:
RXN-8853
|
|
|
|
4-hydroxybenzoate + 5-phospho-alpha-D-ribose_1-diphosphate + H+ <=> 4-(beta-D-ribofuranosyl)hydroxybenzene_5''-phosphate + CO2 + diphosphate
|
2.4.2.54
beta-ribofuranosylphenol 5'-phosphate synthase
|
–
|
| |
BRENDA:
BR50429
KEGG:
R11102
MetaCyc:
RXN-8124
|
|
|
|
7,8-dihydrofolate + NAD+ <=> folate + NADH + H+
|
1.5.1.3
dihydrofolate reductase
|
–
|
| |
KEGG:
R02235
|
|
|
|
7,8-Dihydroneopterin_3''-triphosphate + H2O <=> 2,5-Diamino-6-(5''-triphosphoryl-3'',4''-trihydroxy-2''-oxopentyl)-amino-4-oxopyrimidine
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
| |
KEGG:
R04639
|
|
|
|
5,6,7,8-tetrahydromethanopterin + NADP+ <=> 7,8-dihydromethanopterin + NADPH + H+
|
1.5.1.47
dihydromethanopterin reductase [NAD(P)+]
|
–
|
| |
BRENDA:
BR50394
KEGG:
R03388
MetaCyc:
RXN-10029
|
|
|
|
6-hydroxymethyl-7,8-dihydropterin_diphosphate + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + diphosphate
|
2.5.1.15
dihydropteroate synthase
|
–
|
| |
BRENDA:
BR47663
KEGG:
R03067
MetaCyc:
H2PTEROATESYNTH-RXN
SABIO-RK:
2910
|
|
|
|
tetrahydrobiopterin + NAD+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADH + H+
|
1.5.1.34
6,7-dihydropteridine reductase
|
–
|
| |
BRENDA:
BS319540-a;
BS402604
KEGG:
R01793
MetaCyc:
RXN-14245_WOP
SABIO-RK:
1882
|
|
|
|
tetrahydrofolate + H2O <=> tetrahydrofolate + L-glutamate
|
3.4.19.9
folate gamma-glutamyl hydrolase
|
–
|
| |
KEGG:
R04242
MetaCyc:
RXN-3741
|
|
|
|
Formamidopyrimidine_nucleoside_triphosphate + H2O <=> 2,5-diaminopyrimidine_nucleoside_triphosphate + formate
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
| |
KEGG:
R05046
|
|
|
|
pre-queuine_1 + NADP+ <=> 7-cyano-7-carbaguanine + NADPH + H+
|
1.7.1.13
preQ1 synthase
|
–
|
| |
BRENDA:
BR48717
KEGG:
R07605
MetaCyc:
RXN0-4022
SABIO-RK:
13537
|
|
|
|
cyclic_pyranopterin_phosphate + 2 Thiocarboxy-[sulfur-carrier_protein] <=> molybdopterin + 2 Sulfur-carrier_protein
|
2.8.1.12
molybdopterin synthase
|
–
|
| |
KEGG:
R09395
|
|
|
|
L-tryptophan + tetrahydrobiopterin + O2 <=> 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
1.14.16.4
tryptophan 5-monooxygenase
|
–
–
|
| |
BRENDA:
BS386547
KEGG:
R07213
SABIO-RK:
8593
|
|
|
|
7-carboxy-7-carbaguanine + NH3 + ATP <=> H+ + 7-cyano-7-carbaguanine + ADP + phosphate + H2O
|
6.3.4.20
7-cyano-7-deazaguanine synthase
|
–
|
| |
BRENDA:
BR50022
KEGG:
R09978
MetaCyc:
RXN-12093
|
|
|
|
5,6,7,8-tetrahydromethanopterin + acceptor <=> 7,8-dihydromethanopterin + reduced_acceptor
|
1.5.99.15
dihydromethanopterin reductase (acceptor)
|
–
|
| |
KEGG:
R10802
MetaCyc:
RXN-15555
|
|
|
|
dihydrobiopterin + NADP+ <=> sepiapterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.53
3alpha(or 20beta)-hydroxysteroid dehydrogenase
|
–
–
–
|
| |
BRENDA:
BR29218
KEGG:
R02975
MetaCyc:
SEPIAPTERIN-REDUCTASE-RXN
SABIO-RK:
2829
|
|
|
|
molybdenum_cofactor + GTP + H+ <=> molybdopterin_guanine_dinucleotide + diphosphate
|
2.7.7.77
molybdenum cofactor guanylyltransferase
|
–
|
| |
BRENDA:
BR49476
KEGG:
R11581
MetaCyc:
RXN0-262
SABIO-RK:
15315
|
|
|
|
6-(1''-Hydroxy-2''-oxopropyl)-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.213
3alpha-hydroxysteroid 3-dehydrogenase (Re-specific)
|
–
–
|
| |
KEGG:
R11763
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP <=> H+ + 6-hydroxymethyl-7,8-dihydropterin_diphosphate + AMP
|
2.7.6.3
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
|
–
|
| |
BRENDA:
BR47856
KEGG:
R03503
MetaCyc:
H2PTERIDINEPYROPHOSPHOKIN-RXN
SABIO-RK:
3292
|
|
|
|
5,6,7,8-tetrahydromethanopterin + L-glutamate + ATP <=> H+ + tetrahydrosarcinapterin + ADP + phosphate
|
6.3.2.33
tetrahydrosarcinapterin synthase
|
–
|
| |
BRENDA:
BR49212
KEGG:
R09594
MetaCyc:
RXN-11103
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate + H2O <=> 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + tripolyphosphate + H+
|
4.1.2.50
6-carboxytetrahydropterin synthase
|
–
|
| |
BRENDA:
BR50066
KEGG:
R09959
MetaCyc:
RXN0-5507
|
|
|
|
1''-hydroxy-2''-oxopropyltetrahydropterin + NADPH <=> tetrahydrobiopterin + NADP+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.21
aldose reductase
|
–
–
|
| |
BRENDA:
BS383524
KEGG:
R11764
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 6-pyruvoyltetrahydropterin + tripolyphosphate + H+
|
4.2.3.12
6-pyruvoyltetrahydropterin synthase
|
–
|
| |
BRENDA:
BR48350
KEGG:
R04286
MetaCyc:
4.2.3.12-RXN
SABIO-RK:
9435
|
|
|
|
H+ + 6-carboxy-5,6,7,8-tetrahydropterin <=> 7-carboxy-7-carbaguanine + NH3
|
4.3.99.3
7-carboxy-7-deazaguanine synthase
|
–
|
| |
BRENDA:
BR50129
KEGG:
R10002
MetaCyc:
RXN0-6575
|
|
|
|
7,8-dihydroneopterin_2,3''-cyclic_phosphate + H2O <=> H+ + 7,8-dihydroneopterin_2''-phosphate
|
3.1.4.56
7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
|
–
|
| |
BRENDA:
BR50444
KEGG:
R10345
MetaCyc:
RXN-12357
|
|
|
|
GTP + H2O <=> 7,8-dihydroneopterin_2,3''-cyclic_phosphate + formate + diphosphate + H+
|
3.5.4.16
GTP cyclohydrolase I
3.5.4.39
GTP cyclohydrolase IV
|
–
–
|
| |
BRENDA:
BR50468
KEGG:
R10348
MetaCyc:
RXN-10063
|
|
|
|
(8S)-3,8-cyclo-7,8-dihydroguanosine_5''-triphosphate <=> cyclic_pyranopterin_phosphate + diphosphate
|
4.6.1.17
cyclic pyranopterin monophosphate synthase
|
–
|
| |
BRENDA:
BR51778
KEGG:
R11372
MetaCyc:
RXN-17809
|
|
|
|
ATP + tetrahydrofolate + L-glutamate <=> ADP + phosphate + 5,6,7,8-tetrahydropteroyl-Glu2
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
| |
BRENDA:
BS369045;
BS369050
KEGG:
R00942
|
|
|
|
molybdenum_cofactor + CTP + H+ <=> molybdopterin_cytosine_dinucleotide + diphosphate
|
2.7.7.76
molybdenum cofactor cytidylyltransferase
2.7.7.77
molybdenum cofactor guanylyltransferase
|
–
–
|
| |
BRENDA:
BR49474
KEGG:
R11582
MetaCyc:
RXN0-6254
SABIO-RK:
15295;
15314
|
|
|
|
chorismate + L-glutamine <=> 4-amino-4-deoxychorismate + L-glutamate
|
2.6.1.85
aminodeoxychorismate synthase
|
–
|
| |
BRENDA:
BR47979
KEGG:
R01716
MetaCyc:
PABASYN-RXN
SABIO-RK:
1828
|
|
|
|
tetrahydrobiopterin + NADP+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
–
|
| |
BRENDA:
BS319540;
BS388536
KEGG:
R01794;
R11765
MetaCyc:
RXN-14245
SABIO-RK:
1883;
7757
|
|
|
|
H+ + molybdopterin + ATP <=> adenylyl-molybdopterin + diphosphate
|
2.7.7.75
molybdopterin adenylyltransferase
|
–
|
| |
BRENDA:
BR49475
KEGG:
R09726
MetaCyc:
RXN-8344
|
|
|
|
7,8-dihydroneopterin_3''-phosphate <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde_phosphate
|
4.1.2.59
dihydroneopterin phosphate aldolase
|
–
|
| |
BRENDA:
BR52079
KEGG:
R11718
MetaCyc:
RXN-18378
|
|
|
|
H2O + GTP <=> H+ + diphosphate + 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate + formate
|
3.5.4.25
GTP cyclohydrolase II
|
–
|
| |
BRENDA:
BR26117
KEGG:
R00425
MetaCyc:
GTP-CYCLOHYDRO-II-RXN
SABIO-RK:
880
|
|
|
|
4-amino-4-deoxychorismate <=> H+ + 4-Aminobenzoic_acid + pyruvate
|
4.1.3.38
aminodeoxychorismate lyase
|
–
|
| |
BRENDA:
BR47975
KEGG:
R05553
MetaCyc:
ADCLY-RXN
|
|
|
|
biopterin + NADPH + H+ <=> dihydrobiopterin + NADP+
|
1.5.1.33
pteridine reductase
|
–
|
| |
BRENDA:
BS426034
KEGG:
R12644
|
|
|
|
molybdenum_cofactor + L-cysteine + reduced_acceptor <=> MoOS(OH)Dtpp-mP + L-alanine + H2O + acceptor
|
2.8.1.9
molybdenum cofactor sulfurtransferase
|
–
|
| |
KEGG:
R11583
MetaCyc:
RXN-21548
|
|
|
|
7,8-dihydroneopterin <=> glycolaldehyde + 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine
|
4.1.2.25
dihydroneopterin aldolase
|
–
|
| |
BRENDA:
BR357
KEGG:
R03504
MetaCyc:
H2NEOPTERINALDOL-RXN
SABIO-RK:
3293
|
|
|
|
L-tyrosine + tetrahydrobiopterin + O2 <=> L-Dopa + 4a-hydroxytetrahydrobiopterin
|
1.14.16.2
tyrosine 3-monooxygenase
|
–
|
| |
BRENDA:
BS377086
KEGG:
R07212
SABIO-RK:
7156
|
|
|
|
tetrahydrofolate + L-glutamate + ATP <=> tetrahydrofolate + ADP + phosphate
|
6.3.2.17
tetrahydrofolate synthase
|
–
|
| |
BRENDA:
BR109
KEGG:
R04241
MetaCyc:
FOLYLPOLYGLUTAMATESYNTH-RXN
|
|
|
|
tetrahydrobiopterin + NADP+ <=> biopterin + NADPH + H+
|
1.5.1.33
pteridine reductase
|
–
|
| |
BRENDA:
BR43855
KEGG:
R01812
MetaCyc:
1.1.1.253-RXN
SABIO-RK:
1898
|
|
|
|
7,8-Dihydroneopterin_3''-triphosphate + 3 H2O <=> 7,8-dihydroneopterin + 3 phosphate
|
3.1.3.1
alkaline phosphatase
|
–
|
| |
KEGG:
R04620
|
|
|
|
folate + NADPH <=> tetrahydrofolate + NADP+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
–
|
| |
BRENDA:
BS259283
KEGG:
R00940
SABIO-RK:
1256
|
|
|
|
tetrahydro-L-threo-neopterin + NADP+ <=> H+ + 7,8-dihydro-L-monapterin + NADPH
|
1.5.1.34
6,7-dihydropteridine reductase
1.5.1.50
dihydromonapterin reductase
|
–
–
|
| |
BRENDA:
BR51347
KEGG:
R11019
MetaCyc:
RXN0-6367
|
|
|
|
7,8-dihydroneopterin_2,3''-cyclic_phosphate + H2O <=> H+ + 7,8-dihydroneopterin_3''-phosphate
|
3.1.4.56
7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase
|
–
|
| |
BRENDA:
BR50443
KEGG:
R10344
MetaCyc:
RXN-12356
|
|
|
|
S-adenosyl-L-methionine + GTP + reduced_acceptor <=> (8S)-3,8-cyclo-7,8-dihydroguanosine_5''-triphosphate + L-methionine + 5''-deoxyadenosine + acceptor + H+
|
4.1.99.22
GTP 3',8-cyclase
|
–
|
| |
KEGG:
R09394
MetaCyc:
RXN-8340
|
|
|
|
tetrahydrobiopterin + NADP+ <=> (6R)-L-erythro-6,7-dihydrobiopterin + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
–
|
| |
BRENDA:
BS319540;
BS388536
KEGG:
R01794;
R11765
MetaCyc:
RXN-14245
SABIO-RK:
1883;
7757
|
|
|
|
(6R)-L-erythro-6,7-dihydrobiopterin <=> dihydrobiopterin
|
not assigned
|
–
|
| |
KEGG:
R11767
MetaCyc:
RXN-21000
|
|
|
|
adenylyl-molybdopterin + molybdate + H+ <=> molybdenum_cofactor + AMP + H2O
|
2.10.1.1
molybdopterin molybdotransferase
|
–
|
| |
BRENDA:
BR49440
KEGG:
R09735
MetaCyc:
RXN-8348
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde_triphosphate
|
4.1.2.60
dihydroneopterin triphosphate aldolase
|
–
|
| |
BRENDA:
BR52078
KEGG:
R11719
MetaCyc:
RXN-18377
|
|
|
|
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADPH + H+ <=> tetrahydrobiopterin + NADP+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
|
–
|
| |
BRENDA:
BS187320
KEGG:
R01813
|
|
|
|
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone_5'-phosphate <=> 7,8-dihydroneopterin_3''-phosphate + H2O
|
4.2.1.160
2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one isomerase/dehydratase
|
–
|
| |
BRENDA:
BR51538
KEGG:
R11072
MetaCyc:
RXN-15730
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate + H2O <=> H+ + 7,8-dihydroneopterin_3''-phosphate + diphosphate
|
3.6.1.67
dihydroneopterin triphosphate diphosphatase
|
–
|
| |
BRENDA:
BR51137
KEGG:
R04638
MetaCyc:
H2NEOPTERINP3PYROPHOSPHOHYDRO-RXN
SABIO-RK:
10428
|
|
|
|
7,8-dihydroneopterin_3''-phosphate + H2O <=> 7,8-dihydroneopterin + phosphate
|
3.6.1
|
–
|
| |
KEGG:
R04621
MetaCyc:
DIHYDRONEOPTERIN-MONO-P-DEPHOS-RXN
|
|
|
|
7,8-dihydroneopterin_3''-triphosphate <=> 7,8-dihydromonapterin_3'-triphosphate
|
5.1.99.7
dihydroneopterin triphosphate 2'-epimerase
5.1.99.8
7,8-dihydroneopterin epimerase
|
–
–
|
| |
BRENDA:
BR51427
KEGG:
R11082
MetaCyc:
H2NTPEPIM-RXN
|
|
|
|
7,8-dihydrofolate + NADH + H+ <=> tetrahydrofolate + NAD+
|
1.5.1.3
dihydrofolate reductase
|
–
|
| |
BRENDA:
BS424618
KEGG:
R00936
SABIO-RK:
1254
|
|
|
|
pyrimidodiazepine + GSSG + H2O <=> 6-pyruvoyltetrahydropterin + glutathione
|
1.5.4.1
pyrimidodiazepine synthase
|
–
|
| |
BRENDA:
BR40353
KEGG:
R03984
MetaCyc:
1.5.4.1-RXN
|
|
|
|
L-threo-tetrahydrobiopterin + 2 NADP+ <=> 6-pyruvoyltetrahydropterin + 2 NADPH + 2 H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.325
sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
|
–
–
|
| |
BRENDA:
BR50020
KEGG:
R09990
|
|
|
|
tetrahydrofolate + NADP+ <=> 7,8-dihydrofolate + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
1.5.1.34
6,7-dihydropteridine reductase
1.5.1.50
dihydromonapterin reductase
|
–
–
–
–
|
| |
BRENDA:
BR36900
KEGG:
R00939
MetaCyc:
DIHYDROFOLATEREDUCT-RXN;
RXN-19329
|
|
|
|
7,8-dihydroneopterin + acceptor <=> neopterin + reduced_acceptor
|
not assigned
|
–
|
| |
KEGG:
R04622
|
|
|
|
GTP + H2O <=> Formamidopyrimidine_nucleoside_triphosphate
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
| |
KEGG:
R00428
|
|
|
|
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin <=> sepiapterin
|
not assigned
|
–
|
| |
KEGG:
R11766
|
|
|
|
2-Amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 4-Aminobenzoic_acid <=> 7,8-dihydropteroate + H2O
|
2.5.1
2.5.1.15
dihydropteroate synthase
|
–
–
|
| |
KEGG:
R03066
MetaCyc:
RXN-14226
|
|
|
|
7,8-dihydrofolate + NADP+ <=> folate + NADPH + H+
|
1.5.1.3
dihydrofolate reductase
1.5.1.33
pteridine reductase
|
–
–
|
| |
KEGG:
R02236
MetaCyc:
RXN-18357
SABIO-RK:
2207
|
|
|
|
1'-oxo-2'-L-hydroxypropyl-tetrahydropterin + NADP+ <=> 6-pyruvoyltetrahydropterin + NADPH + H+
|
1.1.1.153
sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming)
1.1.1.184
carbonyl reductase (NADPH)
1.1.1.21
aldose reductase
1.1.1.220
6-pyruvoyltetrahydropterin 2'-reductase
|
–
–
–
–
|
| |
BRENDA:
BR29261
KEGG:
R04285
|
|
|
|
L-phenylalanine + tetrahydrobiopterin + O2 <=> L-tyrosine + 4a-hydroxytetrahydrobiopterin
|
1.14.16.1
phenylalanine 4-monooxygenase
|
–
|
| |
BRENDA:
BS386541
KEGG:
R07211
SABIO-RK:
8496
|
|
|
|
L-glutamate + 7,8-dihydropteroate + ATP <=> H+ + 7,8-dihydrofolate + phosphate + ADP
|
6.3.2.12
dihydrofolate synthase
6.3.2.17
tetrahydrofolate synthase
|
–
–
|
| |
BRENDA:
BR104
KEGG:
R02237
MetaCyc:
DIHYDROFOLATESYNTH-RXN
|
|
|
|
2,5-diaminopyrimidine_nucleoside_triphosphate <=> 2,5-Diamino-6-(5''-triphosphoryl-3'',4''-trihydroxy-2''-oxopentyl)-amino-4-oxopyrimidine
|
3.5.4.16
GTP cyclohydrolase I
|
–
|
| |
KEGG:
R05048
|
|
|
|
folate + NADH <=> tetrahydrofolate + NAD+
|
1.5.1.3
dihydrofolate reductase
1.5.1.34
6,7-dihydropteridine reductase
|
–
–
|
| |
BRENDA:
BS319536-a
KEGG:
R00937
|
|
